Cell Biophysics Laboratory

Cell Biophysics Lab
Principal Investigator: Aranda-Espinoza, Helim
Location: 3135 Jeong H. Kim Engineering Building

The Cell Biophysics Laboratory applies the theoretical and experimental machinery of physics and engineering to obtain a quantitative understanding of specific problems inspired by biological systems. The group studies the mechanics and motility of healthy cells, as well as those of cells with pathological conditions. Of particular interest for the group is to understand how the mechanical environment dictates cell functions.

Control of Miniaturized Systems for Mechatronic, Biological, and Clinical Applications Laboratory

Control of Miniaturized Systems for Mechatronic, Biological, and Clinical Applications Laboratory
Principal Investigator: Shapiro, Ben
Location: 3178 Glenn L. Martin Hall

Modeling, design, and control of micro- and nano-scale systems and flows for bio-chemical and clinical applications. The Shapiro Group chooses applications where control can dramatically improve or allow new capabilities, and focuses on areas that will allow better diagnosis and treatment of people. Current projects range from precision and gentle control of individual cells on chip, e.g. for cell handling, sorting, and complex sample preparation, to control of magnetic nano-particles in people, for drug delivery to the inner ear and to primary and metastatic tumors. (Above: Feedback control of magnetic fields to focus chemotherapy coated nano-particles to deep tissue tumors.)

Eichhorn Research Group

Zintl Clusters
Principal Investigator: Eichhorn, Bryan

The Eichhorn Research Group's current interests include solid oxide fuel cells (material design and discovery, extensive characterization, catalytic and electrocatalytic analysis and prototype development), nanoparticle catalysis (selectively preparing and fully characterizing bimetallic nanoparticles in different architectures), zintl clusters, and matalloid clusters (development of aluminum monohalide chemistry).

Functional Macromolecular Laboratory

Intelligent packaging film changing colors.
Principal Investigator: Kofinas, Peter
Briber, Robert M.
Location: 1211-1213 Jeong H. Kim Engineering Building

The Functional Macromolecular Laboratory focuses on the synthesis, characterization and processing of novel polymer-based nanostructured systems used in a variety of technological fields, ranging from medicine and pharmaceuticals to energy storage and microelectronics. The lab features a comprehensive set of characterization equipment for polymer mechanical, thermal, dielectric, conductive properties. Current projects include the design of polymers, hydrogels, and molecularly imprinted polymers (MIPs) for use in blood-coagulation, intelligent food packaging capable of detecting pathogenic bacteria, hemodialysis, vaccine production, the selective binding of viruses and proteins, and electrolytes for flexible batteries and energy storage systems. Equipment includes a differential scanning calorimeter (DSC), dynamic mechanical analyzer (DMA) dielectric analyzer (DEA), ultraviolet/visible light spectrophotometer, gel permeation chromatography with light scattering (GPC), ultramicrotome with cryo capability, and frequency response analyzer (FRA).

See Also: Polymer Characterization Laboratory

Laboratory for MicroTechnologies

Laboratory for MicroTechnologies
Principal Investigator: Smela, Elisabeth
Location: 2176 Martin Hall

The Laboratory for MicroTechnologies focuses on developing new technologies at the micro-scale that combine conventional inorganic materials and devices with organic, polymeric, and biological materials or living cells. Group members work in the area of cell-based sensing, in close collaboration with Professor Abshire, in which cells are cultured onto CMOS/MEMS devices and monitored using a range of sensing modalities. One application is an olfactory sensory neuron based bionose-on-a-chip. Associated technologies include microfluidics and dielectrophoresis (DEP). The group also has extensive experience with polymeric "artificial muscles," including microfabricated conjugated polymer actuators, dielectric elastomer actuators, and a new type of hydraulic "nastic" actuator. In addition, lab members are developing compliant electrodes for use with these actuators and flexible electronics. The lab features equipment for driving and characterizing actuators, for characterizing thin films, and for handling cells.

MEMS Sensors and Actuators Laboratory (MSAL)

Principal Investigator: Ghodssi, Reza
Location: 2201 J. M. Patterson Building

The MEMS Sensors and Actuators Laboratory (MSAL) focuses on the design, fabrication, and testing of self-sustaining adaptive integrated bio-microsystems for chemical and biological sensing. The devices are designed using a variety of both in-house and commercial simulation software packages and developed utilizing state-of-the-art micro and nano fabrication and characterization techniques. Current projects include microfluidic-based opto-mechanical platforms for monitoring bacterial quorum sensing, next generation battery and fuel cell devices using the tobacco mosaic virus (TMV), and integrated III-V optical microsystems for chemical vapor sensing.

Sang Bok Lee Research Group

Principal Investigator: Lee, Sang Bok
Location: 2112, 3113 and 3115 Chemistry Building

Professor Lee's expertise in nanomaterials synthesis and electrochemistry forms the foundation of his research program. The Lee Group is, in general, interested in the synthesis of 1-D nanotubular and nanowire structures with various materials, since the 1-D structure has many attributes that other nanostructures do not have. The group is also interested in application of these various 1-D naostructures in the biomedical, materials, and energy fields. Current research projects may be categorized into three major areas: (1) synthesis and characterization of nanotube structures with various electronic and/or electrochemical materials and their application to ultrafast electrochromic display and high-power energy storage devices, (2) synthesis and characterization of bio-nanotubes for biomedical applications such as targeted drug delivery and biosensors, and (3) investigation of fundamental physical and chemical properties of nanostructured  materials such as diffusion and reaction problems in a confined geometry of silica nanotube.

Wang Group

Principal Investigator: Wang, Chunsheng
Location: Rooms 4122, 4126, and 4128 Chemistry Building

The Wang Group's research activities focus on four areas: Li-ion batteries, Na-ion batteries, alkaline fuel cells, and electroanalytical techniques, covering topics from fundamental electrochemistry and materials synthesis to electrochemical devices. Current projects include novel electroanalytical techniques for phase transformation electrodes, virus enabled anodes for Li-ion batteries, scaffold Si-based anodes for Li-ion batteries, synthesis of alkaline anion exchange membranes (AAEMs) for fuel cell and metal-air battery applications, and addressing the challenges associated with the development of high energy density Li-S, Na-S, and Li-air batteries.

Zachariah Lab

Zachariah Lab
Principal Investigator: Zachariah, Michael

The Zachariah Lab's mission is to understand and manipulate from a fundamental standpoint the physical and chemical phenomena in the formation and application of nanoscale materials. Current projects include aerosol based processing to create new nanomaterials for energy, and the environment; the development of new instrumentation for the characterization of nanoparticles relevant to energy, the environment and nanomedicine; and the development and application of molecular based modeling tools for understanding gas-to-particle conversions and nanoparticle properties.